Sepsis related neurological complications / 中国小儿急救医学

The central nervous system ( CNS) complications and peripheral nervous system ( PNS) complications are common complications of sepsis. CNS complications include sepsis associated encephalopathy (SAE),septic-metastatic encephalitis (SME),and septic-embolic encephalitis (SEE). Of them,the SAE is the most common complication of CNS complications. PNS complications include critical illness polyneuropathy (CIP) and critical illness myopathy (CIM). CIP and CIM could lead to muscle weakness and dependence on mechanical ventilation of patients with sepsis. Sepsis related neurological complications are closely related to the mortality and prognosis of patients,so early recognition and timely intervention are important.

Concomitant Acute Transverse Myelitis and Sensory Motor Axonal Polyneuropathy in Two Children: Two Case Reports

Acute transverse myelitis (ATM) is an upper motor neuron disease of the spinal cord, and concomitant association of peripheral polyneuropathy, particularly the axonal type, is rarely reported in children. Our cases presented with ATM complicated with axonal type polyneuropathy. Axonal type polyneuropathy may be caused by acute motor-sensory axonal neuropathy (AMSAN) or critical illness polyneuropathy and myopathy (CIPNM). These cases emphasize the need for nerve and muscle biopsies to make the differential diagnosis between AMSAN and CIPNM in patients with ATM complicated with axonal polyneuropathy.